Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
Toxicologic Pathology
This Article
Right arrow Free Full Text (Free PDF) Free
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Taylor, D. L.
Right arrow Articles by Farkas, D. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Taylor, D. L.
Right arrow Articles by Farkas, D. L.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Journal Article

Potential of Machine-Vision Light Microscopy in Toxicologic Pathology

D. Lansing Taylor

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Robbin DeBiasio

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Greg LaRocca

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

David Pane

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Penny Post

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

John Kolega

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Ken Giuliano

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Kevin Burton

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Bert Gough

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Alasdair Dow

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Judy Yu

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Alan S. Waggoner

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Daniel L. Farkas

Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213

Major developments in machine-vision light microscopy and in reagent chemistry have led to a renaissance and revolution in the use of the light microscope in biology, biotechnology, and medicine. The potential use of this technology in the field of toxicologic pathology is discussed. It is suggested that a combination of investigating living cells and tissues and fixed samples using the new technologies will lead to understanding mechanisms of toxicity. Examples of the use of the methods in basic cell biology and medicine are presented.

Key Words: Fluorescence • 3-dimensional microscopy • video-enhanced contrast • in situ hybridization • immunofluorescence • fluorescent analogs

Toxicologic Pathology, Vol. 22, No. 2, 145-159 (1994)
DOI: 10.1177/019262339402200208
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Toxicol PatholHome page
B. Mccullough, Xiaoyou Ying, T. Monticello, and M. Bonnefoi
Digital Microscopy Imaging and New Approaches in Toxicologic Pathology
Toxicol Pathol, February 1, 2004; 32(2_suppl): 49 - 58.
[Abstract] [PDF]