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Toxicologic Pathology
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Current Methods for Assessing Safety of Genetically Modified Crops as Exemplified by Data on Roundup Ready 1 Soybeans

Rashmi S. Nair

Monsanto Company, 800 N. Lindbergh Blvd, St. Louis, Missouri 63167, rashmi.s.nair{at}Monsanto.com.

Roy L. Fuchs

Monsanto Company, 800 N. Lindbergh Blvd, St. Louis, Missouri 63167

Sheila A. Schuette

Monsanto Company, 800 N. Lindbergh Blvd, St. Louis, Missouri 63167

Several laboratories have used recombinant DNA technology in plant breeding to improve compositional, processing, and agronomic characteristics of plants. These transformed plants have been extensively tested in fi eld trials, have gained full regulatory approvals and are currently being marketed in a number of countries around the world. This paper briefl y summarizes the approach used to assure the safety of foods and feeds derived from these genetically modified crops, as exemplified by data on Roundup Ready soybeans that has been developed by Monsanto Company using biotechnology in order to confer tolerance to glyphosate, the active ingredient in Roundup herbicide, by the production of the CP4 enolpyruvylshikimate-3-phosphate synthase protein. The results of the studies demonstrate that Roundup Ready soybeans are as safe as traditional soybeans with respect to food and feed safety.

Key Words: Genetically modified foods • safety assessments • soybeans.

Toxicologic Pathology, Vol. 30, No. 1, 117-125 (2002)
DOI: 10.1080/01926230252824806
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