Toxicologic Pathology

 

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Toxicologic Pathology, Vol. 30, No. 2, 288-291 (2002)
DOI: 10.1080/019262302753559632

Pulmonary Sequestration with Ectopic Pancreatic Tissue in a Wistar Hannover GALAS Rat

Yukiko Takeuchi

Laboratory of Pathology, Toxicology Division Institute of Environmental Toxicology, Uchimoriya-machi 4321, Mitsukaido-shi, Ibaraki 303-0043, Japan, takeuchi{at}iet.or.jp

Toshinori Yoshida

Laboratory of Pathology, Toxicology Division Institute of Environmental Toxicology, Uchimoriya-machi 4321, Mitsukaido-shi, Ibaraki 303-0043, Japan

Yuko Chiba

Laboratory of Pathology, Toxicology Division Institute of Environmental Toxicology, Uchimoriya-machi 4321, Mitsukaido-shi, Ibaraki 303-0043, Japan

Maki Kuwahara

Laboratory of Pathology, Toxicology Division Institute of Environmental Toxicology, Uchimoriya-machi 4321, Mitsukaido-shi, Ibaraki 303-0043, Japan

Keizo Maita

Division of Study Planning and Consultation, Institute of Environmental Toxicology, Uchimoriya-machi 4321, Mitsukaido-shi, Ibaraki 303-0043, Japan

Takanori Harada

Laboratory of Pathology, Toxicology Division Institute of Environmental Toxicology, Uchimoriya-machi 4321, Mitsukaido-shi, Ibaraki 303-0043, Japan

A multicystic mass of the lung was found in a male 11-week-ol d Wistar Hannover GALAS rat. The cystic mass was located in the region of the right caudal lobe and had no direct communication with the tracheobranchia l tree. Histologically, the pulmonary mass was composed of variably sized cysts containing mucinous material, cellular debris, erythrocytes, and infl ammatory cells. In the septal stroma between the cysts, well-developed elastic and muscular arteries were present and in some areas, ectopic pancreatic tissue was observed. In the rest of the lung lobes, there was no evidence of previous pneumonic events or other respiratory diseases. Based on these findings, the present case was diagnosed as a congenital pulmonary sequestration with ectopic pancreatic tissue.

Key Words: Lung • congenital • rat • pancreas • sequestration.


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