Toxicologic Pathology

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Register here to gain access to SAGE's 500+ Journals Online

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
0192623307312692v1
36/2/247    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kasahara, K.
Right arrow Articles by Tamura, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kasahara, K.
Right arrow Articles by Tamura, K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
This version was published on February 1, 2008
Toxicologic Pathology, Vol. 36, No. 2, 247-249 (2008)
DOI: 10.1177/0192623307312692

Invited Review

Spontaneous Leiomyosarcoma Arising from the Ethmoid Turbinate of a Rat

Kenichiro Kasahara, Seiki Yamakawa, Mariko Nagatani, Maiko Tsurukame and Kazutoshi Tamura

Division of Pathology, Gotemba Laboratory, Bozo (Biology & Zoology), Research Center Inc., 1284 Kamado, Gotemba, Shizuoka 412–0039, Japan

Correspondence: Address correspondence to: Kenichiro Kasahara, Biology and Zoology Research Center Inc.—Division of Pathology, 1284, Kamado, Gotemba, Shizuoka, Japan 412–0039; e-mail: path-k{at}bozo.co.jp.

Spontaneous leiomyosarcoma arising from the left ethmoid turbinate was observed microscopically in an 83-week-old male F344 rat. The tumor cells showed smooth-muscle differentiation with prominent nuclear pleomorphism and a small number of mitotic figures. The tumor cells were also immunohistochemically positive for smooth-muscle actin. The tumor protruded slightly into the nasal cavity and invaded the surrounding tissues. The present article is the first case of spontaneous leiomyosarcoma in the rat nasal cavity.

Key Words: Leiomyosarcoma • nasal cavity • rat

Abbreviations: HE, hematoxylin and eosin • MFH, malignant fibrous histiocytoma


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?