Toxicologic Pathology

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
0192623308315831v1
36/3/385    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Google Scholar
Right arrow Articles by Ramot, Y.
Right arrow Articles by Nyska, A.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ramot, Y.
Right arrow Articles by Nyska, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
This version was published on April 1, 2008
Toxicologic Pathology, Vol. 36, No. 3, 385-387 (2008)
DOI: 10.1177/0192623308315831

Articles

Foreign-Body Granulomas within Intramyocardial Arteries in a Transcoronary Safety Assessment in Pigs

Yuval Ramot1, Gail Amir2, Ehud P. Willenz3 and Abraham Nyska4

1 Hadassah-Hebrew University Medical Center, Jerusalem, 91120, Israel
2 Department of Pathology, Hadassah—Hebrew University Medical Center, Jerusalem, 91120, Israel
3 Neufeld Cardiac Research Institute, Sheba Medical Center, Tel Hashomer, 5262, Israel
4 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel and Timrat, 36576, Israel

Correspondence: Address correspondence to: Abraham Nyska, D.V.M., Dipl. ECVP, Toxicological Pathologist, Haharuv 18, P.O. Box 184, Timrat, Israel 36576; e-mail:anyska{at}bezeqint.net.

Foreign-body granulomas within intramyocardial arteries were detected in three domestic pigs (Sus scrofa domestica) in a routine transcoronary safety assessment study. The foreign bodies stained light grayish-blue by hematoxylin and eosin (H&E) and were strongly birefringent by polarized light microscopy. By their morphological features, they were identified as cotton fibers. Embolization of foreign-body material into the myocardial arteries following catheter-based procedures is an unusual event, and its occurrence may lead to granulomatous foreign-body reaction and misinterpretation of histological results.

Key Words: granuloma • foreign body • embolization • coronary • angiography


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?