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Toxicologic Pathology
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Journal Article

Sequential Morphological Changes in Aflatoxin B1-Induced Liver Tumors During Chronic Administration of Glutathione

Anna M. Novi

Department of Pathology, Düsseldorf University Düsseldorf, Federal Republic of Germany

Tzanka Boschnakova

Department of Pathology, Düsseldorf University Düsseldorf, Federal Republic of Germany

Waldemar Hort

Department of Pathology, Düsseldorf University Düsseldorf, Federal Republic of Germany

The sequential light microscopic changes in aflatoxin B1-induced liver tumors during chronic administration of glutathione were studied. The results suggest that necrosis of neoplastic hepatocytes plays an important role during the regression of tumor growth induced by glutathione.

  • 1. Novi AM: Regression of aflatoxin B1-induced hepatocellular carcinomas by reduced glutathione. Science 212: 541–542, 1981.[Abstract/Free Full Text]
  • 2. Novi AM: Liver carcinogenesis in rats after aflatoxin B1 administration. A light and electron microscopic study. Curr Top Pathol 65: 115–163, 1977.[Medline] [Order article via Infotrieve]
  • 3. Wogan GN: Aflatoxin carcinogenesis. Methods Cancer Res 7: 309–344, 1973.
  • 4. Benade L, Howard T, Burk D: Synergistic killing of Ehrlich ascites carcinoma cells by ascorbate and 3-amino-1,2,4-triazole. Oncology 23: 33–43, 1969.[Web of Science][Medline] [Order article via Infotrieve]

Toxicologic Pathology, Vol. 10, No. 2, 127-129 (1982)
DOI: 10.1177/019262338201000222
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This Article
Right arrow Abstract Freely available
Right arrow Free Full Text (Free PDF) Free
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Novi, A. M.
Right arrow Articles by Hort, W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Novi, A. M.
Right arrow Articles by Hort, W.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?