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A Congenital Ciliated Epithelial Cyst on the Stomach of a B6C3F 1 Mouse

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Tohru Kihara

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Masayo Hosoi

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Shinji Yamamoto

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Shin-Ichi Mikami

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Seiki Yamakawa

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Hijiri Iwata

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Makoto Enomoto

Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan

Congenital anomalies of the alimentary tract are rare lesions in laboratory animals. We describe a congenital cyst attached to the greater curvature of the forestomach in a B6C3F₁ mouse. The inner surface of the cyst was mostly covered with cuboidal or pseudostratified ciliated epithelium and was focally covered with the flat cuboidal epithelium. The base of the cyst appeared to be inserted between the layers of the outer longitudinal muscle layer of the forestomach, although no smooth muscle layer was evident in the free surface of the cyst wall. The cyst resembled duplication of the alimentary tract, as it was lined with ciliated epithelium and had developed at the greater curvature of the forestomach. Since the smooth muscle layer did not completely cover the whole wall and the cyst did not communicate with the gastric lumen, the cyst was not thought to be a standard duplication but rather a simple congenital cyst.

Key Words: Duplication • mouse • congenital • cyst • ciliated epithelium • stomach

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Toxicologic Pathology, Vol. 27, No. 5, 600-603 (1999)
DOI: 10.1177/019262339902700514


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This Article Abstract Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Miyajima, R. Articles by Enomoto, M. Search for Related Content PubMed PubMed Citation Articles by Miyajima, R. Articles by Enomoto, M. Social Bookmarking                         What's this?