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Endocrine Disruptors: Overview and a Pathologist's Perspective
Sandy Kennedy
Quintiles England Limited, Ledbury, Herefordshire, United Kingdom
Key Words: Endocrine disruptors endocrine modulators testing strategy assays validation
References
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- Ashby J., Lefevre PA, Odum J., Tinwell H., Kennedy SJ, Beresford N., Sumpter JP (1997). Failure to confirm rodent uterotrophic activity for benzoic acid or clofibrate: Implication for lists of endocrine disrupting agents. Regul Toxicol Pharmacol 26: 96-101.[CrossRef][Web of Science][Medline]
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- Bliley R. (1996). Food Quality Protection Act of 1996, 104th Congress, 2nd Session. Report 104-669, Part 2, Government Printing Office, Washington, DC.
- Kennedy SJ (1998). Environmental Oestrogens—An Industry Viewpoint. Hormonally Active Agents in Food. WILEY-VCH, Verlag GmbH, Weinheim, Germany.
- O'Connor JC, Cook JC, Craven SC, Van Pelt CS, Obourn JD (1996). An in vivo battery for identifying endocrine modulators that are estrogenic or dopamine regulators. Fundam Appl Toxicol 33: 182-195.[CrossRef][Web of Science][Medline]
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- Odum J., Lefevre PA, Tittensor S., Paton D., Routledge EJ, Beresford NA, Sumpter JP, Ashby J. (1997). The rodent uterotrophic assay: Critical protocol features, studies with nonyl phenols, and comparison with a yeast estrogenicity assay. Regul Toxicol Pharmacol 25: 176-188.[CrossRef][Web of Science][Medline]
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- Reel JR, Lamb JC. Neal BH (1996). Survey and assessment of mammalian estrogen biological assays for hazard characterisation. Fundam Appl Toxicol 34: 288-305.[CrossRef][Web of Science][Medline]
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- Wakeling AE, Dukes M., Bowler J. (1991). A potent pure antioestrogen with clinical potential. Cancer Res 51: 3867-3873.[Abstract/Free Full Text]
Toxicologic Pathology, Vol. 28, No. 3,
418-419 (2000)
DOI: 10.1177/019262330002800310

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Toxicol Pathol,
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28(3):
370 - 374.
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