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Case Report: Carcinoma of the Extraorbital Lacrimal Gland in a Female Fischer 344 Rat

Southern Research Institute, Birmingham, Alabama, heath{at}serquest.com

F. Rahemtullah

University of Alabama at Birmingham, Birmingham, Alabama

W. David Fine

University of Alabama at Birmingham, Birmingham, Alabama

A large subcutaneous mass was observed at necropsy in the right neck area of a 95-week-old female Fischer 344 rat that served as an untreated control animal in a 2-year carcinogenicity study. Formalin-fixed, paraffin-embedded sections of the mass were stained with hematoxylin and eosin along with the immunohistochemical biomarkers lactoperoxidase, catalase, and amylase. Based on its histomorphological and immunohistochemical features, the lesion was diagnosed as a carcinoma of the extraorbital lacrimal gland.

Key Words: Neoplasm • rat • lacrimal gland • immunocytochemistry • spontaneous

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Toxicologic Pathology, Vol. 28, No. 6, 824-826 (2000)
DOI: 10.1177/019262330002800608


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This Article Abstract Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Heath, J. E. Articles by Fine, W. D. Search for Related Content PubMed PubMed Citation Articles by Heath, J. E. Articles by Fine, W. D. Pubmed/NCBI databases Substance via MeSH Medline Plus Health Information Eye Cancer Social Bookmarking                         What's this?