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Response to "Alternative Models for Carcinogenicity Testing: Weight of Evidence Across Models" Sam Cohen, Toxicologic Pathology (2001) 29(Suppl.): 183—190
Syrian Hamster Embryo Assay Working Group
R.J. Mauthe
Pfizer Global Research and Development, Groton, CT 06340-8014
D.P. Gibson
The Procter and Gamble Company, Cincinnati, OH 45253-8707
R.T. Bunch
Pharmacia Corporation, Skokie, IL 60077
L. Custer
Bristol-Myers Squibb, Inc., P.O. Box 5400, Princeton, NJ 08543
References
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- Gibson DP, Aardema MJ, Kerckaert GA, Brauninger RM, LeBoeuf RA (1995). Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo cell transformation assay. Mutat Res 343: 7—24.[CrossRef][Web of Science][Medline]
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- Isfort RJ, Kerckaert GA, LeBoeuf R.A. (1996a). Comparison of the standard and reduced pH Syrian hamster embryo (SHE) cell in vitro cell transformation assay to predict the carcinogenic potential of chemicals. Mutat Res 356: 11—63.[Web of Science][Medline]
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- Kerckaert GA, Isfort RJ, Carr GJ, Aardema MJ (1996b). A comprehensive protocol for conducting the Syrian hamster embryo cell transformation assay at pH 6.70. Mutat Res 356: 65—84.[Web of Science][Medline]
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- LeBoeuf RA, Kerckaert GA, Poiley J., Raineri R. (1989). An interlaboratory comparison of enhanced morphological transformation of Syrian hamster embryo cells cultured under conditions of reduced bicarbonate concentration and pH. Mutat Res 222: 205—218.[CrossRef][Web of Science][Medline]
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- LeBoeuf RA, Kerckaert GA, Aardema MJ, Isfort RJ (1999). Use of Syrian hamster embryo and BALB/c 3T3 cell transformation for assessing the carcinogenicity potential of chemicals. In: The Use of Short- and Medium-term Tests for Carcinogenic Hazard Evaluation, McGregor DB, Rice JM, Venitt S (eds). IARC Scientific Publications No. 146, pp 409—425.
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- Mussler B., Schwind K-R., Englehardt G. (2001). Evaluation of the Syrian hamster embryonic (SHE) assay as predictive screening Tool in carcinogenic hazard identification. Toxicol Pathol 29(Suppl.): 317—318.
- Swierenga and Yamasaki (1999). Performance of tests for cell transformation and gap-junction intercellular communication for detecting nongentoxic carcinogenic activity. In: Mechanisms of Carcinogenesis in Risk Identification, Vainio H, Magee PN, McGregor DB, McMichael AJ (eds). IARC, Lyon, France, pp 165—193.
Toxicologic Pathology, Vol. 30, No. 2,
292-293 (2002)
DOI: 10.1080/019262302753559641

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