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Toxicologic Pathology
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Diet-Gene Interactions in p53-Deficient Mice: IGF-1 as a Molecular Target

STEPHEN D. HURSTING, 1 JACKIEA. LAVIGNE,1 DAVIDBERRIGAN,1 BARBARA J. DAVIS,2 LARRY A. DONEHOWER,3 J. CARL BARRETT,1 AND SUSAN N. PERKINS, 1 1 National Cancer Institute, Bethesda, Maryland 20892; 2National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709; 3Baylor College of Medicine, Houston, Texas 77030

References

  • Berrigan, D.A., S.N. Perkins, D.C. Haines, and S.D. Hursting (2002). "Adult-Onset Calorie Restriction and Fasting Delay Spontaneous Tumorigenesis in p53-Deficient Mice." Carcinogenesis 23: 817—22.[Abstract/Free Full Text]
  • Calle, E.E., C. Rodriguez, K. Walker-Thurmond, and M.J. Thun (2003). "Overweight, Obesity and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults." New Engl J Med 348: 1625—38.[CrossRef]
  • Dunn, S.E., F. Kari, J. French, J. Leininger, G. Travlos, R. Wilson, and J.C. Barrett (1997). "Dietary Restriction Reduces Insulin-Like Growth Factor-1 Levels Which Modulates Apoptosis, Cell Proliferation, and Tumor Progression in p53 Deficient Mice." Cancer Res 57: 4667—72.[Abstract/Free Full Text]
  • Flegal, K.M., M.D. Carroll, C.L. Ogden, and C.L. Johnson (2002). "Prevalence and Trends in Obesity Among US Adults, 1999—2000." J Am Med Assoc 288: 1723—27.[Abstract/Free Full Text]
  • Hursting, S.D. and R.A. Lubet (2001). The utility of transgenic mice in cancer prevention studies. Tumor Models in Cancer Research. B. Teicher. Humana Press, Inc, Totowa, NJ.
  • Hursting, S.D., S.N. Perkins, C.C. Brown, D.C. Haines, and J.M. Phang (1997). "Calorie Restriction Induces a p53-Independent Delay of Spontaneous Carcinogenesis in p53-Deficient and Wild-Type Mice. Cancer Res 57: 2843—6.[Abstract/Free Full Text]
  • Hursting, S.D., S.N. Perkins, and J.M. Phang (1994). "Calorie Restriction Delays Spontaneous Tumorigenesis in p53-Knockout Mice." Proc Natl Acad Sci USA 91: 7036—40.[Abstract/Free Full Text]
  • Hursting, S.D., T.J. Slaga, S.M. Fischer, J. DiGiovanni, and J.M. Phang (1999). "Mechanism-Based Cancer Prevention Approaches: Targets, Examples and the Use of Transgenic Mice." J Natl Cancer Inst 91: 215—25.[Abstract/Free Full Text]
  • Perkins, S.N., S.D. Hursting, D.C. Haines, S.J. James, and J.M. Phang (1997). "Chemoprevention of Spontaneous Tumorigenesis in Nullizygous p53-Deficient Mice by Dehydroepiandrosterone and its Analog, 16-{alpha}-fluoro-5-androsten-17-one." Carcinogenesis 18: 101—6.
  • Poetschke, H.L., D.B. Klug, S.N. Perkins, E.R. Richie, and S.D. Hursting (2000). "The Effects of Calorie Restriction on Thymocyte Growth, Death and Maturation." Carcinogenesis 21: 1959—64.[Abstract/Free Full Text]

Toxicologic Pathology, Vol. 32, No. 1, 140-141 (2004)
DOI: 10.1080/714592163


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This Article
Right arrow Free Full Text (Free PDF) Free
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Right arrow Email this article to a friend
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Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
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 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?