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Session 3: Risk Assessment
References
- U.S. Environmental Protection Agency. (2003 ). Draft Final Guidelines for Carcinogen Risk Assessment. NCEA-F-0644A. Washington, DC, 125 pp.
- Atsdr. Toxicological profile for 1,3-butadiene. Benzene. (1992). Agency for Toxic Substances and Disease Registery, U.S. Department of Health and Human Services, Public Health Service.
- Melnick, R.L., Huff, J., Chou, B.J., and Miller, R.A. (1990). Carcinogenicity of 1,3-Butadiene in C57Bl/6Xc3H F1-Mice at Low Exposure Concentrations. Cancer Research 50, 6592—9.[Abstract/Free Full Text]
- Owen, P.E., Glaister, J.R., Gaunt, I.F., and Pullinger, D.H. (1987). Inhalation toxicity studies with 1,3-butadiene. 3. Two year toxicity/carcinogenicity study in rats. Am. Ind. Hyg. Assoc. J. 48, 407—13.[Web of Science][Medline]
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- Delzell, E., Sathiakumar, N., Hovinga, M., Macaluso, M., Julian, J., Larson, R., Cole, P., and Muir, D.C. (1996). A follow-up study of synthetic rubber workers. Toxicology 113, 182—9.[CrossRef][Web of Science][Medline]
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- Divine, B.J., and Hartman, C.M. (1996). Mortality update of butadiene production workers. Toxicology 113, 169—81.[CrossRef][Web of Science][Medline]
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- Swenberg, J.A., Koc, H., Upton, P.B., Georgieva, N., Ranasinghe, A., Walker, V.E., and Henderson, R. (2001). Using DNA and hemoglobin adducts to improve the risk assessment of butadiene. Chem. Bio. Inter. 135—136, 387— 403.[CrossRef]
- Jayaraj, K., Georgieva, N.I., Gold, A., Sangaiah, R., Koc, H., Klapper, D.G., Ball, L.M., Reddy, A.P., and Swenberg, J.A. (2003). Synthesis and characterization of peptides containing a cyclic Val adduct of diepoxybutane, a possible biomarker of human exposure to butadiene. Chem Res Toxicol 16, 637—43.[CrossRef][Web of Science][Medline]
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- Ellinger-Ziegelbauer, H., Stuart, B., Wahle, B., Bomann, W., and Hans-Jurgen, A. (2204). Toxicol Sci 77, 19—34.[CrossRef]
- Newton, R., Thybaud, V., Boitier, E., Lynch, A., Harvey, J., Minnick, D., Morris, S., Sistare, F., MacGregor, J., Fornace, A., Amundson, S., Aubrecht, J., Aardema, M., Vanparys, P., Van Goethem, F., Staedtler, F., Mueller, L., Martus, H., and Bolcsfoldi, G. (2003). Assessment of DNA microarrays as a tool for characterizing genotoxicity. Toxicogenomics in Risk Assessment Assessing the Utility, Challenges, and Next Steps. June 5—6, Hyatt Fair Lakes, Virginia.
Toxicologic Pathology, Vol. 32, No. 6,
733-735 (2004)
DOI: 10.1080/01926230490882420

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