James F. Reindel, Gary D. Pilcher, Alexander W. Gough, Jeffrey R. Haskins, and Felix A. De La Iglesia

Recombinant Human Epidermal Growth Factor1-48-Induced Structural Changes in the Digestive Tract of Cynomolgus Monkeys (Macaca fascicularis)
Toxicol Pathol 1996 24: 669-680. [Abstract] [PDF] [References] [Request Permission]  

Laurence O. Whiteley, Leon Hudson, JR, and Theresa P. Pretlow

Aberrant Crypt Foci in the Colonic Mucosa of Rats Treated with a Genotoxic and Nongenotoxic Colon Carcinogen
Toxicol Pathol 1996 24: 681-689. [Abstract] [PDF] [References] [Request Permission]  

Sechi Ito, Chise Tateno, Mina Tuda, and Akira Yoshitake

Immunohistochemical Demonstration of the Gap Junctional Protein Connexin 32 and Proliferating Cell Nuclear Antigen in Glutathione S-Transferase Placental Form-Negative Lesions of Rat Liver Induced by Diethylnitrosamine and Clofibrate
Toxicol Pathol 1996 24: 690-695. [Abstract] [PDF] [References] [Request Permission]  

Hans C. Chen, In J. Pan, Wen J. Tu, Wen H. Lin, Chou C. Hong, and Mavis R. Brittelli

Neoplastic Response in Japanese Medaka and Channel Catfish Exposed to N-Methyl-N'-Nitro-N-Nitrosoguanidine*¹
Toxicol Pathol 1996 24: 696-706. [Abstract] [PDF] [References] [Request Permission]  

Ava C. Logan and Kanwar Nasir M. Khan

Case Report: Clinical Pathologic Changes in Two Marmosets with Wasting Syndrome
Toxicol Pathol 1996 24: 707-709. [Abstract] [PDF] [References] [Request Permission]  

Joel F. Mahler, William Stokes, Peter C. Mann, Masaya Takaoka, and Robert R. Maronpot

Spontaneous Lesions in Aging FVB/N Mice
Toxicol Pathol 1996 24: 710-716. [Abstract] [PDF] [References] [Request Permission]  

Joel F. Mahler, Barbara J. Davis, Scott G. Morham, and Robert Langenbach

Disruption of Cyclooxygenase Genes in Mice
Toxicol Pathol 1996 24: 717-719. [PDF] [References] [Request Permission]  

Peter C. Mann

The Great Mouse Debate: Should the Mouse Continue to Be Used for Carcinogenicity Studies?
Toxicol Pathol 1996 24: 720. [PDF] [Request Permission]  

Jerry F. Hardisty

Value of the Mouse Carcinogenicity Bioassay
Toxicol Pathol 1996 24: 720-721. [PDF] [Request Permission]  

Carl L. Alden, Peter F. Smith, Charles E. Piper, and Leszek Brej

A Critical Appraisal of the Value of the Mouse Cancer Bioassay in Safety Assessment
Toxicol Pathol 1996 24: 722-725. [Abstract] [PDF] [References] [Request Permission]  

R.R. Maronpot and G.A. Boorman

The Contribution of the Mouse in Hazard Identification Studies
Toxicol Pathol 1996 24: 726-731. [Abstract] [PDF] [References] [Request Permission]  

Comments, Questions, and Answers
Toxicol Pathol 1996 24: 732-733. [PDF] [Request Permission]  

Bernard M. Wagner

Book Review: Drug-Induced Neurological Disorders. K. K. Jain, M.D. Seattle: Hogrefe and Huber Publishers. 1996, 389 pp., $79.00
Toxicol Pathol 1996 24: 733. [PDF] [Request Permission]  

Jerrold M. Ward

Rat or Mouse Cancer Bioassay—or None of the Above?
Toxicol Pathol 1996 24: 734-735. [PDF] [References] [Request Permission]  

Bernard M. Wagner

Book Review: Methods in Renal Toxicology. R. K. Zalups and L. H. Lash, Editors. Boca Raton, Florida: CRC Press. 1996, 435 pp., $99.95
Toxicol Pathol 1996 24: 735. [PDF] [Request Permission]  

Kevin P. Keenan

Effect of Food Restriction On Risk Assessment
Toxicol Pathol 1996 24: 736-737. [PDF] [Request Permission]  

Edward J. Masoro

Possible Mechanisms Underlying the Antiaging Actions of Caloric Restriction
Toxicol Pathol 1996 24: 738-741. [Abstract] [PDF] [References] [Request Permission]  

Richard Weindruch

The Retardation of Aging by Caloric Restriction: Studies in Rodents and Primates
Toxicol Pathol 1996 24: 742-745. [Abstract] [PDF] [References] [Request Permission]  

Paul M. Newberne and Alexander V. Sotnikov

Diet: The Neglected Variable in Chemical Safety Evaluations
Toxicol Pathol 1996 24: 746-756. [Abstract] [PDF] [References] [Request Permission]  

Kevin P Keenan, Philippe Laroque, Gordon C. Ballam, Keith A. Soper, Rakesh Dixit, Britta A. Mattson, Stephen P Adams, and John B. Coleman

The Effects of Diet, Ad Libitum Overfeeding, and Moderate Dietary Restriction on the Rodent Bioassay: The Uncontrolled Variable in Safety Assessment
Toxicol Pathol 1996 24: 757-768. [Abstract] [PDF] [References] [Request Permission]  

Angelo Turturro, Peter Duffy, Ronald Hart, and William T. Allaben

Rationale for the Use of Dietary Control in Toxicity Studies—B6C3F1 Mouse
Toxicol Pathol 1996 24: 769-775. [Abstract] [PDF] [References] [Request Permission]  

William T. Allaben, Angelo Turturro, Julian E.A. Leakey, John E. Seng, and Ronald W. Hart

FDA Points-to-Consider Documents: The Need for Dietary Control for the Reduction of Experimental Variability within Animal Assays and the Use of Dietary Restriction to Achieve Dietary Control
Toxicol Pathol 1996 24: 776-781. [Abstract] [PDF] [References] [Request Permission]  

Timothy A. Bertram

Editorial Aberrant Crypt Foci: New Insights into the Early Events of Colon Carcinogenesis Induced by Genotoxic and Nongenotoxic Carcinogens
Toxicol Pathol 1996 24: 782-783. [PDF] [References] [Request Permission]  

Roger Brown

The American Registry of Pathology 20th Anniversary Celebration and Board Meeting May 22-23 1996
Toxicol Pathol 1996 24: 784. [PDF] [Request Permission]  

Peter C. Mann

XV International Symposium of the Society of Toxicologic Pathologists Poster Abstracts
Toxicol Pathol 1996 24: 787-796. [PDF] [Request Permission]  

Adalbert Koestner

Robert W. Leader, D.V.M., M.S. (1919-1996)
Toxicol Pathol 1996 24: 797-798. [PDF] [Request Permission]  

J. Hartke

"Have You Seen This?" Bone Anti-Resorptive Properties of Bisphosphonates
Toxicol Pathol 1996 24: 799-800. [PDF] [References] [Request Permission]  

R.R. Maronpot

A Symposium Summary and Perspective on Comparative Molecular Biology of Cancer
Toxicol Pathol 1996 24: 801-804. [PDF] [Request Permission]  

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