Toxicologic Pathology -- Table of Contents (January 2004, 32 [1])

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Contents: January 2004, Volume 32, No. 1 [Index by Author] Other Issues:

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Miwa Okamura, Takao Watanabe, Yoko Kashida, Noboru Machida, and Kunitoshi Mitsumori: Possible Mechanisms Underlying the Testicular Toxicity of Oxfendazole in Rats
Toxicol Pathol 2004 32: 1-8. [Abstract] [PDF] [References]

Veit-Simon Eckle, Albrecht Buchmann, Wilfried Bursch, Rolf Schulte-Hermann, and Michael Schwarz: Immunohistochemical Detection of Activated Caspases in Apoptotic Hepatocytes in Rat Liver
Toxicol Pathol 2004 32: 9-15. [Abstract] [PDF] [References]

Thai-Vu T. Ton, Hue-Hua L. Hong, Colleen H. Anna, June K. Dunnick, Theodora R. Devereux, Robert C. Sills, and Yongbaek Kim: Predominant K-ras Codon 12 G $->$ A Transition in Chemically Induced Lung Neoplasms in B6C3F1 Mice
Toxicol Pathol 2004 32: 16-21. [Abstract] [PDF] [References]

Richard D. Verschoyle, Richard Edwards, Barbara Nolan, and Peter Greaves: Articular Chondromatosis and Chrondroid Metaplasia in Transgenic TAg Mice
Toxicol Pathol 2004 32: 22-25. [Abstract] [PDF] [References]

Laurel Gregory, James J. Pestka, Dorr G. Dearborn, and Thomas G. Rand: Localization of Satratoxin-G in Stachybotrys chartarum Spores and Spore-Impacted Mouse Lung Using Immunocytochemistry
Toxicol Pathol 2004 32: 26-34. [Abstract] [PDF] [References]

Philip H. Long, Ronald A. Herbert, and Abraham Nyska: Hexachlorobenzene-Induced Incisor Degeneration in Sprague—Dawley Rats
Toxicol Pathol 2004 32: 35-40. [Abstract] [PDF] [References]

Yoshiro Tani, Robert R. Maronpot, Julie F. Foley, Joseph K. Haseman, Nigel J. Walker, and Abraham Nyska: Follicular Epithelial Cell Hypertrophy Induced by Chronic Oral Administration of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Female Harlan Sprague—Dawley Rats
Toxicol Pathol 2004 32: 41-49. [Abstract] [PDF] [References]

Klára Szentmihályi, Erzsébet Fehér, Péter Vinkler, Ágnes Kéry, and Anna Blázovics: Metabolic Alterations of Toxic and Nonessential Elements by the Treatment of Sempervivum tectorum Extract in a Hyperlipidemic Rat Model
Toxicol Pathol 2004 32: 50-57. [Abstract] [PDF] [References]

Michael V. Pino, Michael F. Kelley, and Zaid Jayyosi: Promotion of Colon Tumors in C57BL/6J-APCmin/+ Mice by Thiazolidinedione PPAR ${gamma}$ Agonists and a Structurally Unrelated PPAR ${gamma}$ Agonist
Toxicol Pathol 2004 32: 58-63. [Abstract] [PDF] [References]

Xing Cui, Song Li, Amjad Shraim, Yayoi Kobayashi, Toru Hayakawa, Sanae Kanno, Megumi Yamamoto, and Seishiro Hirano: Subchronic Exposure to Arsenic Through Drinking Water Alters Expression of Cancer-Related Genes in Rat Liver
Toxicol Pathol 2004 32: 64-72. [Abstract] [PDF] [References]

Maria T. Gallardo-Williams, Robert E. Chapin, Paula E. King, Glenda J. Moser, Thomas L. Goldsworthy, James P. Morrison, and Robert R. Maronpot: Boron Supplementation Inhibits the Growth and Local Expression of IGF-1 in Human Prostate Adenocarcinoma (LNCaP) Tumors in Nude Mice
Toxicol Pathol 2004 32: 73-78. [Abstract] [PDF] [References]

Norman J. Barlow, Barry S. Mcintyre, and Paul M.D. Foster: Male Reproductive Tract Lesions at 6, 12, and 18 Months of Age Following in Utero Exposure to Di(n-butyl) Phthalate
Toxicol Pathol 2004 32: 79-90. [Abstract] [PDF] [References]

J. Mark Cline, Adrian A. Franke, Thomas C. Register, Deborah L. Golden, and Michael R. Adams: Effects of Dietary Isoflavone Aglycones on the Reproductive Tract of Male and Female Mice
Toxicol Pathol 2004 32: 91-99. [Abstract] [PDF] [References]

Silke Burkhardt, Rainer Bahnemann, Klaus Failing, and Manfred Reinacher: Zonal Distribution of Cell Proliferation in the Liver of Untreated B6C3F1 and C57BL Mice
Toxicol Pathol 2004 32: 100-105. [Abstract] [PDF] [References]

Kendall B. Wallace, Elizabeth Hausner, Eugene Herman, Gordon D. Holt, James T. Macgregor, Alan L. Metz, Elizabeth Murphy, I.Y. Rosenblum, Frank D. Sistare, and Malcolm J. York: Serum Troponins as Biomarkers of Drug-Induced Cardiac Toxicity
Toxicol Pathol 2004 32: 106-121. [PDF] [References]

Darrell Tuomari, Glenn Elliott, Barbara Kulwich, John Yarrington, Xavier Fouillet, Frank Geoly, and Philip Long: Society of Toxicologic Pathology Position on Histopathology Data Collection and Audit Trail: Compliance with 21 CFR Parts 58 and 11
Toxicol Pathol 2004 32: 122-123. [Abstract] [PDF]

: Society of Toxicologic Pathology Position on Assessment of Hyperplastic Lesions in Rodent Carcinogenicity Studies
Toxicol Pathol 2004 32: 124-125. [PDF] [References]

James W. Crissman, Dawn G. Goodman, Paul K. Hildebrandt, Robert R. Maronpot, Donald A. Prater, Julia H. Riley, William J. Seaman, and Daryl C. Thake: Best Practices Guideline: Toxicologic Histopathology
Toxicol Pathol 2004 32: 126-131. [PDF] [References]

Benjamin F. Trump: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy: July 20—23, 2003, The Gant Conference Center, Aspen, Colorado
Toxicol Pathol 2004 32: 132-134. [PDF]

: SESSION 1: CHROMATIN REMODELING Chromatin Remodeling 2003: WILLIAM R. BRINKLEY, Department of Molecular and Cellular Biology and the Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030
Toxicol Pathol 2004 32: 135. [PDF]

: ATP-Dependent Chromatin Remodeling Complexes for Transcription CARL WU, Laboratory of Molecular Cell Biology, Centerfor Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-4255
Toxicol Pathol 2004 32: 135-136. [PDF] [References]

: Evolution of Imprinted Tumor Susceptibility Genes: RANDY L. JIRTLE, Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710
Toxicol Pathol 2004 32: 136-137. [PDF] [References]

: Session 2: Molecular Diagnostics: Molecular Diagnostics: Chairman's Introduction JOHN F. LECHNER, Office of Technology for Diagnostics Systems, Bayer Diagnostics, Berkeley, California 94702
Toxicol Pathol 2004 32: 137-138. [PDF] [References]

: Genetic and Epigenetic Alterations in Cancer Detection: DAVID SIDRANSKY, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196
Toxicol Pathol 2004 32: 138-139. [PDF] [References]

: Diagnostic Arrays for Epigenetic Markers: YU-WEI LEU AND TIM H.-M. HUANG, Human Cancer Genetics Program, The Ohio State University Comprehensive Cancer Center, Medical Research Facility, Columbus, Ohio 43210
Toxicol Pathol 2004 32: 139. [PDF] [References]

: Session 3: Cancer Prevention: Prevention of Liver Cancer THOMAS W. KENSLER, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205
Toxicol Pathol 2004 32: 139-140. [PDF] [References]

: Diet-Gene Interactions in p53-Deficient Mice: IGF-1 as a Molecular Target: STEPHEN D. HURSTING, 1 JACKIEA. LAVIGNE,1 DAVIDBERRIGAN,1 BARBARA J. DAVIS,2 LARRY A. DONEHOWER,3 J. CARL BARRETT,1 AND SUSAN N. PERKINS, 1 1 National Cancer Institute, Bethesda, Maryland 20892; 2National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709; 3Baylor College of Medicine, Houston, Texas 77030
Toxicol Pathol 2004 32: 140-141. [PDF] [References]

: Engineering Cancer Resistance in Mice: MANUEL SERRANO, ANDER MATHEU, AND ISABEL GARCIA-CAO, Spanish National Center of Biotechnology, Campus de Cantoblanco, Madrid 28049, Spain
Toxicol Pathol 2004 32: 141. [PDF] [References]

: SESSION 4: THERAPY Cancer Therapy 2003: Current State of the Century: PAUL A. BUNN, JR., University of Colorado Cancer Center, Denver, Colorado 80262
Toxicol Pathol 2004 32: 141-142. [PDF] [References]

: Progesterone, Estrogens, and their Receptors in Breast Cancers KATHRYN B. HORWITZ, Departments of Medicine, Pathology and the Molecular Biology Program, University of Colorado School of Medicine, Denver, Colorado
Toxicol Pathol 2004 32: 142-143. [PDF] [References]

: Inflammation, Dietary Carcinogens, Glutathione S-Transferase ${pi}$ , and Prostatic Carcinogenesis: WILLIAM G. NELSON, ANGELO M. DE MARZO, THEODORE L. DEWEESE, AND WILLIAM B. ISAACS, The Departments of Oncology, Urology, Pathology, Pharmacology, and Medicine, The Johns Hopkins University School of Medicine, and The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
Toxicol Pathol 2004 32: 143-144. [PDF] [References]

: Telomerase, Cell Mortality, and GRN163—A Potent and Specific Telomerase Inhibitor for Cancer Therapy: CALVIN B. HARLEY, Geron Corporation, Menlo Park, California 94025
Toxicol Pathol 2004 32: 144. [PDF]

: KEYNOTE SPEAKER Nuclear Cloning and the Reversibility of Cancer: RUDOLF JAENISCH, ROBERT BLELLOCH, KONRAD HOCHEDLINGER, AND KEVIN EGGAN, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, 02142
Toxicol Pathol 2004 32: 144-145. [PDF]

: Session 5: Telomeres: Telomere Looping: A Conserved Theme Across all Eukaryotes? LUBOMIR TOMASKA,1 SMARANDA WILLCOX,2 ANTHONY CESARE,2 NICOLE FOUCHE,2 NANCY QUINNEY,2 DEEPA SUBRAMANIAN,2 AND JACK GRIFFITH2. 1 Department of Genetics and Biochemistry, Comenius University, Bratislava, Slovakia, and 2the Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599-7295
Toxicol Pathol 2004 32: 145-146. [PDF] [References]

: Telomere Replication and Cellular Senescence: YING ZOU, WOODRING E. WRIGHT, AND JERRY W. SHAY, Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9039
Toxicol Pathol 2004 32: 146. [PDF] [References]

: Telomeres and Telomerase in Homeostasis and Cancer: STEVEN E. ARTANDI, KAVITA SARIN, AND EUNICE LEE, Department of Hematology, Cancer Biology Program, Stanford University School of Medicine, Stanford, California 94305-5156
Toxicol Pathol 2004 32: 146-147. [PDF] [References]

: Session 6: Stem Cells: Contribution of Stem Cells and Differentiated Cells to Tumours of the Epidermis FIONA M. WATT, CR-UK London Research Institute, London WC2A 3PX, England
Toxicol Pathol 2004 32: 147-148. [PDF] [References]

: Functional Characterization of Mammary Stem Cells: JEFFREY M. ROSEN,1 BRYAN E. WELM,3 STACEY B. TEPERA,1 SANDRA L. GRIMM,1 TERESA VENEZIA,2 MARGARET A. GOODELL,2 TIMOTHY A. GRAUBERT,4 ZENA WERB,3 YI LI,5, 6 AND HAROLD E. VARMUS,6 1 Department of Molecular and Cellular Biology; 2 Center for Cell and Gene Therapy and Department of Pediatrics; 5 Baylor Breast Center, Baylor College of Medicine, Houston, Texas 77030; 3Department of Anatomy, University of California, San Francisco, California 94143; 4Division of Bone Marrow Transplantation and Stem Cell Biology, Washington University School of Medicine, St. Louis, Missouri 63110; and 6 Memorial Sloan Kettering Cancer Center, New York, NY 10021
Toxicol Pathol 2004 32: 148-149. [PDF] [References]

: SESSION 7: FUNCTIONAL GENOMICS Functional Genomics: RAYMOND TENNANT, National Center for Toxicogenomics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina
Toxicol Pathol 2004 32: 149. [PDF] [References]

: Toxicogenomics: ROGER G. ULRICH, Department of Molecular Profiling, Rosetta Inpharmatics-Merck Research Laboratories, Kirkland, Washington 98034
Toxicol Pathol 2004 32: 149-150. [PDF] [References]

: The Future is Now: Oncology Pharmacogenetics and Pharmacogenomics Reach the Bedside: JEFFREY S. ROSS, Division of Molecular Medicine, Millennium Pharmaceuticals, Cambridge, Massachusetts 02139 and Department of Pathology, Albany Medical College, Albany, New York
Toxicol Pathol 2004 32: 150-152. [PDF] [References]

: Session 8: Imaging/Tumor Dormancy: Imaging TONA M. GILMER, Department of Oncology Biology, GlaxoSmithKline, Research Triangle Park, North Carolina 27709
Toxicol Pathol 2004 32: 152. [PDF] [References]

: Imaging Proteolysis in Living Organotypic Models of Cancer: BONNIE F. SLOANE, MANSOUREH SAMENI, STEFANIE ROSHY, IZABELA PODGORSKI, JULIE DOSESCU, BRUCE LINEBAUGH, MICHAEL CHER, AND KAMIAR MOIN, Departments of Pharmacology, Urology and Pathology, Wayne State University and Proteases and Cancer Program, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201
Toxicol Pathol 2004 32: 152-153. [PDF] [References]

: Molecular Imaging of Gene Expression and Protein Function In Vivo: Cancer Drug Targets and Drug Resistance: DAVID PIWNICA-WORMS, Molecular Imaging Center, Mallinckrodt Institute of Radiology, Department of Molecular Biology and Pharmacology, Washington University Medical School, St. Louis, Missouri
Toxicol Pathol 2004 32: 153. [PDF] [References]

: SESSION 9: PARADOXES IN SAFETY ASSESSMENT Paradoxes in Safety Assessment: Animal Carcinogen? Human Carcinogen?—Chairman's Introduction: WILLIAM H. FARLAND, Office of Research and Development, United States Environmental Protection Agency, Washington, DC 20460
Toxicol Pathol 2004 32: 154. [PDF] [References]

: Mechanism of Carcinogenicity of Vinyl Acetate: MATTHEW S. BOGDANFFY,1 R. CLARK LANTZ,2 JAMES E. MELVIN,3 AND RUDY VALENTINE,1 1DuPont Haskell Laboratory, P.O. Box 50, Newark, Delaware; 2 University of Arizona, Tuscon, Arizona; 3 University of Rochester Medical Center, Rochester, New York
Toxicol Pathol 2004 32: 154-155. [PDF] [References]

: Atrazine: A Sprague—Dawley Rat-Specific Mammary Carcinogen: JAMES A. SWENBERG, Laboratory of Molecular Carcinogenesis and Mutagenesis, University of North Carolina, Chapel Hill, North Carolina 27599
Toxicol Pathol 2004 32: 155-156. [PDF] [References]

: YOUNG INVESTIGATORS' ABSTRACTS Preferential Binding of High Mobility Group Protein, HMG-1, to Triplex DNA: MADHAVA C. REDDY AND KAREN M. VASQUEZ, Department of Carcinogenesis, University of Texas, M. D. Anderson Cancer Center, Science Park-Research Division, Smithville, Texas 78957
Toxicol Pathol 2004 32: 157. [PDF] [References]

: The Phosphorylation State of p53 Alters its DNA Damage Recognition Properties: DEEPA SUBRAMANIAN AND JACK D. GRIFFITH, Lineberger Comprehensive Cancer Center and Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599
Toxicol Pathol 2004 32: 158. [PDF] [References]

: Expression of Base Excision DNA Repair Genes is a Sensitive Biomarker for In Vivo Detection of Chemical-Induced Chronic Oxidative Stress: IVAN RUSYN, SHOJI ASAKURA, AND JAMES A. SWENBERG, Department of Environmental Sciences and Engineering, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599
Toxicol Pathol 2004 32: 158-159. [PDF] [References]

: Cathepsin B in the Development of Mammary Acini in Vitro: STEFANIE ROSHY, MANSOUREH SAMENI, JENNIFER KOBLINSKI, AND BONNIE F. SLOANE, Department of Pharamacology and Karmanos Cancer Institutte, Wayne State University, Detroit, Michigan 48201 and the Craniofacial Developmental Biology and Regeneration Branch, NIDCR, National Institutes of Health, Bethesda, Maryland 20892
Toxicol Pathol 2004 32: 159-160. [PDF] [References]

: Association of SULT1A1 Phenotype and Genotype with Prostate Cancer Risk in African Americans and Caucasians: SUSAN NOWELL, D. LUKE RATNASINGHE, SUZANNE WILLIAMS, TERRI TEAGUE-ROSS, LINDSAY TRIMBLE, BRIDGETT GREEN, ANGIE STONE, GRAHAM GREENE, CHRISTINE B. AMBROSONE, NICHOLAS P. LANG, AND FRED F. KADLUBAR, National Center for Toxicological Research, Jefferson, Arkansas 72079; Central Arkansas Veteran's Healthcare System, Little Rock, Arkansas 72205 and University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205
Toxicol Pathol 2004 32: 160. [PDF] [References]

: Effects of Insulin-Like Growth Factor-I Administration on Body Composition and Gene Expression in Calorie Restricted Mice: JACKIE A. LAVIGNE, STEPHEN D. HURSTING, DAVID BERRIGAN, SUSAN N. PERKINS, AND J. CARL BARRETT, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, 20892-4264
Toxicol Pathol 2004 32: 161. [PDF] [References]

: Curcumin Derivatives: Potential for Prostate Cancer Management: ADDANKI P. KUMAR, GRETCHEN E. GARCIA, RITA GHOSH, RAJENDRAN V. RAJNARAYANAN,1 WILLIAM L. ALWORTH,1 AND THOMAS J. SLAGA, Center for Cancer Causation and Prevention, AMC Cancer Research Center and University of Colorado Comprehensive Cancer Center, Denver, Colorado 80214; 1 Department of Chemistry, Tulane University, New Orleans, Louisiana 70118
Toxicol Pathol 2004 32: 161-163. [PDF] [References]

: Gene Expression Profiling of Node-Negative Breast Tumors Reveals Metastatic Recurrence Risk: ANAND IMMANENI, ANNA TSIMELZON, SUSAN G. HILSENBECK, CRAIG ALLRED, PETER O'CONNELL, AND WILLIAM R. BRINKLEY, Breast Center, Department of Molecular and Cellular Biology, Department of Pathology at the Baylor College of Medicine, Houston, Texas 77030
Toxicol Pathol 2004 32: 163. [PDF] [References]

: p53-Mediated Oxidative Stress and Apoptosis: S. PERWEZ HUSSAIN, PAUL AMSTAD, PEIJUN HE, ANA ROBLES, SHAWN LUPOLD, SAGAR SENGUPTA, MASATO ICHIMIYA, SHU OKAMURA, MATHEW MOAKE, KATHLEEN FORRESTER, AND CURTIS C. HARRIS, Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland 20892
Toxicol Pathol 2004 32: 163-164. [PDF] [References]

: The Rational Design of Genotoxins that Selectively Destroy Hormone Receptor-Positive Breast and Prostate Cancers SHAWN M. HILLIER, JOHN C. MARQUIS, KAUSHIK K. MITRA, PETER T. RYE, ARLETTE N. DINAUT, UDAY SHARMA, DENISE C. RODRIGUES, CHARLES I. MORTON, ROSA G. LIBERMAN, PAUL L. SKIPPER, JOHN S. WISHNOK, STEVEN R. TANNENBAUM, JOHN M. ESSIGMANN, AND ROBERT G. CROY, Department of Chemistry and Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
Toxicol Pathol 2004 32: 164-165. [PDF] [References]

: Use of RNAi to Investigate Eµ-myc Lymphomagenesis and Lymphoma Chemoresistance: MICHAEL T. HEMANN AND SCOTT W. LOWE, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724
Toxicol Pathol 2004 32: 165. [PDF] [References]

: Genomic Response of Saccharomyces cerevisiae to Radical Mediated DNA Damage: JOSEPH P. COSGROVE, THOMAS J. BEGLEY, AND PETER C. DEDON, Division of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
Toxicol Pathol 2004 32: 166. [PDF] [References]

: Defense Against Oxidants and Electrophiles Mediated Through the Keap1-Nrf2 System: Analysis of Keap1 Knockout Mice: NOBUNAO WAKABAYASHI1 AND MASAYUKI YAMAMOTO2, Department of Environmental Health Sciences, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 and 2Centers for Tsukuba Advanced Research Alliance, University of Tsukuba, Tennoudai, Tsukuba 305-8577, Japan
Toxicol Pathol 2004 32: 166-167. [PDF] [References]

: Erratum
Toxicol Pathol 2004 32: 168-169. [PDF]

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