Keynote Lecture:

Paul B. Watkins

Idiosyncratic Liver Injury: Challenges and Approaches
Toxicol Pathol 2005 33: 1-5. [Abstract] [Full Text] [PDF]  

Articles:

John M. Cullen

Mechanistic Classification of Liver Injury
Toxicol Pathol 2005 33: 6-8. [Abstract] [Full Text] [PDF]  

Philip F. Solter

Clinical Pathology Approaches to Hepatic Injury
Toxicol Pathol 2005 33: 9-16. [Abstract] [Full Text] [PDF]  

Donna M. Dambach, Barbara A. Andrews, and Frederic Moulin

New Technologies and Screening Strategies for Hepatotoxicity: Use of In Vitro Models
Toxicol Pathol 2005 33: 17-26. [Abstract] [Full Text] [PDF]  

David E. Malarkey, Kennita Johnson, Linda Ryan, Gary Boorman, and Robert R. Maronpot

New Insights into Functional Aspects of Liver Morphology
Toxicol Pathol 2005 33: 27-34. [Abstract] [Full Text] [PDF]  

Jerry F. Hardisty and Amy E. Brix

Comparative Hepatic Toxicity: Prechronic/Chronic Liver Toxicity in Rodents
Toxicol Pathol 2005 33: 35-40. [Abstract] [Full Text] [PDF]  

Harihara M. Mehendale

Tissue Repair: An Important Determinant of Final Outcome of Toxicant-Induced Injury
Toxicol Pathol 2005 33: 41-51. [Abstract] [Full Text] [PDF]  

John R. Foster

Spontaneous and Drug-Induced Hepatic Pathology of the Laboratory Beagle Dog, the Cynomolgus Macaque and the Marmoset
Toxicol Pathol 2005 33: 63-74. [Abstract] [Full Text] [PDF]  

Jeffrey C. Wolf and Marilyn J. Wolfe

A Brief Overview of Nonneoplastic Hepatic Toxicity in Fish
Toxicol Pathol 2005 33: 75-85. [Abstract] [Full Text] [PDF]  

Ingrid M. Pruimboom-Brees, Dominique J. J. E. Brees, Amy C. Shen, Mary Keener, Omar Francone, David E. Amacher, James K. Loy, and Roy L. Kerlin

Using Laser Scanning Cytometry to Measure PPAR-Mediated Peroxisome Proliferation and β Oxidation
Toxicol Pathol 2005 33: 86-91. [Abstract] [Full Text] [PDF]  

Pierre Chaurand, Sarah A. Schwartz, Michelle L. Reyzer, and Richard M. Caprioli

Imaging Mass Spectrometry: Principles and Potentials
Toxicol Pathol 2005 33: 92-101. [Abstract] [Full Text] [PDF]  

Gary A. Boorman, Richard D. Irwin, Molly K. Vallant, Diane K. Gerken, Edward K. Lobenhofer, Milton R. Hejtmancik, Patrick Hurban, April M. Brys, Greg S. Travlos, Joel S. Parker, and Christopher J. Portier

Variation in the Hepatic Gene Expression in Individual Male Fischer Rats
Toxicol Pathol 2005 33: 102-110. [Abstract] [Full Text] [PDF]  

Irwin D. Richard, Joel S. Parker, Edward K. Lobenhofer, Leo T. Burka, Pamela E. Blackshear, Molly K. Vallant, Edward H. Lebetkin, Diane F. Gerken, and Gary A. Boorman

Transcriptional Profiling of the Left and Median Liver Lobes of Male F344/N Rats Following Exposure to Acetaminophen
Toxicol Pathol 2005 33: 111-117. [Abstract] [Full Text] [PDF]  

Mollisa M. Elrick, Jeffrey A. Kramer, Carl L. Alden, Eric A. G. Blomme, Roderick T. Bunch, Marc A. Cabonce, Sandra W. Curtiss, Larry D. Kier, Kyle L. Kolaja, Charles P. Rodi, and Dale L. Morris

Differential Display in Rat Livers Treated for 13 Weeks with Phenobarbital Implicates a Role for Metabolic and Oxidative Stress in Nongenotoxic Carcinogenicity
Toxicol Pathol 2005 33: 118-126. [Abstract] [Full Text] [PDF]  

David E. Malarkey, Joel S. Parker, Coral A. Turman, Allyson M. Scott, Richard S. Paules, Jennifer Collins, and Robert R. Maronpot

Microarray Data Analysis of Mouse Neoplasia
Toxicol Pathol 2005 33: 127-135. [Abstract] [Full Text] [PDF]  

Kevin T. Morgan, Zaid Jayyosi, Moira A. Hower, Michael V. Pino, Timothy M. Connolly, Katja Kotlenga, Jieyi Lin, Min Wang, Hans-Ludwig Schmidts, Marc S. Bonnefoi, Timothy C. Elston, and Gary A. Boorman

The Hepatic Transcriptome as a Window on Whole-Body Physiology and Pathophysiology
Toxicol Pathol 2005 33: 136-145. [Abstract] [Full Text] [PDF]  

Terry S. Peters

Do Preclinical Testing Strategies Help Predict Human Hepatotoxic Potentials?
Toxicol Pathol 2005 33: 146-154. [Abstract] [Full Text] [PDF]  

William M. Lee and John R. Senior

Recognizing Drug-Induced Liver Injury: Current Problems, Possible Solutions
Toxicol Pathol 2005 33: 155-164. [Abstract] [Full Text] [PDF]  

James R. Hailey, Nigel J. Walker, Donald M. Sells, Amy E. Brix, Michael P. Jokinen, and Abraham Nyska

Classification of Proliferative Hepatocellular Lesions in Harlan Sprague–Dawley Rats Chronically Exposed to Dioxin-Like Compounds
Toxicol Pathol 2005 33: 165-174. [Abstract] [Full Text] [PDF]  

Yongbaek Kim, Robert C. Sills, and Chris D. Houle

Overview of the Molecular Biology of Hepatocellular Neoplasms and Hepatoblastomas of the Mouse Liver
Toxicol Pathol 2005 33: 175-180. [Abstract] [Full Text] [PDF]  

Diego F. Calvisi and Snorri S. Thorgeirsson

Molecular Mechanisms of Hepatocarcinogenesis in Transgenic Mouse Models of Liver Cancer
Toxicol Pathol 2005 33: 181-184. [Abstract] [Full Text] [PDF]  

Invited Review:

George A. Parker and Catherine A. Picut

Liver Immunobiology
Toxicol Pathol 2005 33: 52-62. [Abstract] [Full Text] [PDF]  

Abstracts:

Dai Nakae, Fumiyuki Uematsu, Yutaka Hatanaka, Yoichi Konishi, Akihiko Maekawa, Masakazu Takahashi, Midori Yoshida, J. Todd Painter, Corrie Lane, Laura Chubb, Stephen Benjamin, Hongbo Liu, Youchun Jiang, Jie Liu, Min-Liang Cheng, Y. James Kang, Gye Hyeong Woo, G. H. Woo, K. Katayama, E. J. Bak, Uetsuka, H. Nakayama, K. Doi, Miriam R. Anver, Bradley Carlson, Sergey Novoselov, Easwari Kumaraswamy, Byeong Lee, Vadim Gladyshev, Dolph Hatfield, Jan Klapwijk, Yasuko Baba, Koji Uetsuka, Hiroyuki Nakayama, Kunio Doi, Koji Uetsuka, Hirofumi Yamauchi, Hiroyuki Nakayama, Kunio Doi, Alys Bradley, Julie Foley, Jennifer Collins, Robert Maronpot, Cindy Afshari, An Vynckier, Roland De Coster, Johan Verbeeck, Adriana Looszova, Katelijne Anciaux, Tom Verhaeghe, Lieve Lammens, Nini Bode, Werner Coussement, Pablo Aviles, Terence Appelqvist, Jennifer Spedick, David Malarkey, Kennita Johnson, Linda Ryan, G. Allan Johnson, Gary Boorman, Robert Maronpot, Vito Sasseville, Reine Note, Mukesh Patel, Carol Marchant, Nigel Greene, Tanasa Osborne, Kathleen Heinz-Taheny, Wanda Haschek-Hock, Carol Trempus, Robert Maronpot, JoAnn Schuh, Kazuyoshi Kumagai, Takanori Maejima, Toshihiko Makino, Mayumi Watanabe, Seiya Ogata, Munehiro Teranishi, Jo Anne Johnson, June Dunnick, John Horton, Abraha Nyska, Abraham Nyska, Tish Murphy, Julie Foley, Deloris Sutton, Bradley Collins, June Dunnick, Chandikumar Elangbam, Ruth Lightfoot, Robert Geske, Crumbley Christopher, Lawrence Yoon, Denise Fillman-Holliday, Yoshiro Tani, Jack B. Bishop, Kristine L. Witt, Jo Anne Johnson, Shyamal D. Peddada, June K. Dunnick, Abraham Nyska, John Seely, Gordon Hard, Andrew Suttie, Kimwa Walker, Theleria Hackett, Thomas Goldsworthy, Robert Maronpot, Kevin Keane, Abraham Nyska, Donald M. Sells, Amy Brix, Micheal Jokinen, Denise Orzech, Micheal Wyde, Joseph Haseman, Gordon Flake, Nigel Walker, Banalata Sen, Dianne Creasy, Sean McKeag, Ann Williams, Yoshiro Tani, Andrew Suttie, Gordon P. Flake, Abraham Nyska, Robert R. Maronpot, Yoshiro Tani, Robert C. Sills, Paul M. D. Foster, Po-Chuen Chan, Abraham Nyska, Wayne Anderson, Rick Perry, Byron Boysen, James Inhelder, Hiroshi Satoh, Julie Foley, John L. Horton, June Dunnick, David E. Malarkey, R. Maxwell, R. Burden, A. Coyle, Kathleen Heinz-Taheny, Wanda Haschek-Hock, Carol Trempus, Robert Maronpot, Michael Goedken, Sylvain De Guise, Bhanu Pratap Singh, L. K. Singhal, R. S. Chauhan, Michael Orr, B. W. Higgs, K. R. Johnson, A. L. Castle, D. L. Mendrick, Takayuki Tsuchiya, Fumiko Sano, Tetsuya Sakairi, Miyoko Okada, Mamoru Mutai, Toshimi Usui, Jirou Sugimoto, Shirou Takagi, Amy Brix, Abraham Nyska, Joseph Haseman, Donald Sells, Michael Jokinen, Nigel Walker, Maria Cristina de Vera Mudry, Stefan Ruepp, Dong Deuk Jang, Wan-Seob Cho, Beom Seok Han, Cheul Kyu Kim, Ki Taek Nam, Ki Dae Park, Mina Choi, Ki Hwa Yang, Diana Haines, Mahtab Moayeri, Stephen Leppla, Howard Young, Georgina Miller, Aaron Firoved, Mahtab Moayeri, Wei-Jen Tang, Yuequan Shen, Stephen Leppla, Kimberley Cohen, Katsuhiko Yoshizawa, Katsuji Kiuchi, Kaei Moriguchi, Yuji Oishi, Nobuaki Shikata, Airo Tsubura, Elmarie Bodes, Jun Nakamura, Jae-Sung Kim, Brian Pachkowski, John Lemasters, James Swenberg, Shih-Hsuan (Vincent) Hsiao, Peter D. Constable, M. E. Tumbleson, Wanda Haschek-Hock, Rajesh Kumar, Lokesh Singhal, R. S. Chauhan, Vito Sasseville, Arek Raczynski, Vilmos Csizmadia, William Riordan, James Ironside, Page Bouchard, Penelope Fenner-Crisp, Dorothy Patton, William Jordan, Jamie Young, Glenda Moser, Thomas Goldsworthy, Steven H. Nye, Nicholas V. Cozzi, Jordan F. Baye, April Wittenburg, Sally Korb, Richard Roman, Howard J. Jacob, Marcus Jackson, Isabel Lea, Asif Rashid, June Dunnick, Gabrielle Willson, Todd Joron, Gail Pearse, Jerry Hardisty, Gail Pearse, Todd Joron, Gabrielle Willson, Jerry Hardisty, Xiaoyou Ying, Jean-Guy Bienvenu, Michael Pino, Magali Guffroy, Hans-Ludwig Schmidts, Thomas Monticello, Etsuko Fujii, Masami Suzuki, Atsuhiko Kato, Yayoi Karasawa, Yumie Ogawa, Kenji Adachi, Tetsuro Sugimoto, Abraham Nyska, Eran Blaugrund, Adi Mayk, Emanuel Raymond, Yoshiro Tani, Nira Russek, Miri Horowitz, Vered Behar, Vered Behar, Yoni Nadler, Anya Vainshtein, Yona Grunfeld, Nati Ezov, Opher Gileadi, Connie Cummings, Abraham Nyska, and Sundeep Chandra

P1 Altered Expression of Gene Products Involved as a Complex in the Endogenous Hepatocarcinogenesis of Rats Fed a Choline-Deficient, L-Amino Acid-Defined Diet
Toxicol Pathol 2005 33: 185-203. [Full Text] [PDF]  

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